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Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P

tRNAs are typically transcribed with extended 5′ and 3′ ends that must be removed before they attain their active form. One of the first steps of tRNA processing in nearly every organism is the removal of the 5′ leader sequence by ribonuclease P (RNase P). Here, we investigate a recently discovered...

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Detalles Bibliográficos
Autores principales: Wilhelm, Catherine A., Mallik, Leena, Kelly, Abigail L., Brotzman, Shayna, Mendoza, Johnny, Anders, Anna G., Leskaj, Suada, Castillo, Carmen, Ruotolo, Brandon T., Cianfrocco, Michael A., Koutmos, Markos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652100/
https://www.ncbi.nlm.nih.gov/pubmed/37806495
http://dx.doi.org/10.1016/j.jbc.2023.105327