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Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species

SARS-CoV-2′s genetic plasticity has led to several variants of concern (VOCs). Here we studied replicative capacity for seven SARS-CoV-2 isolates (B.1, Alpha, Beta, Gamma, Delta, Zeta, and Omicron BA.1) in primary reconstituted airway epithelia (HAE) and lung-derived cell lines. Furthermore, to inve...

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Detalles Bibliográficos
Autores principales: Essaidi-Laziosi, Manel, Pérez-Rodríguez, Francisco J., Alvarez, Catia, Sattonnet-Roche, Pascale, Torriani, Giulia, Bekliz, Meriem, Adea, Kenneth, Lenk, Matthias, Suliman, Tasnim, Preiser, Wolfgang, Müller, Marcel A., Drosten, Christian, Kaiser, Laurent, Eckerle, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652112/
http://dx.doi.org/10.1016/j.virusres.2023.199255