Thrombin induces ferroptosis in triple-negative breast cancer through the cPLA2α/ACSL4 signaling pathway

Ferroptosis is a recently identified form of regulated cell death that plays a crucial role in tumor suppression. In this study, we found that F2 (the gene encoding thrombin) was strongly upregulated in breast cancer (BRCA, TCGA Study Abbreviations) compared with normal samples and that lower F2 lev...

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Detalles Bibliográficos
Autores principales: Xu, Shuo, Tuo, Qing-zhang, Meng, Jie, Wu, Xiao-lei, Li, Chang-long, Lei, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652120/
https://www.ncbi.nlm.nih.gov/pubmed/37939630
http://dx.doi.org/10.1016/j.tranon.2023.101817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652120/
https://www.ncbi.nlm.nih.gov/pubmed/37939630
http://dx.doi.org/10.1016/j.tranon.2023.101817

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