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Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles

Ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury, which is a serious clinical condition with no effective pharmacological treatment. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) significantly alleviate kidney IRI; however, the underlying mechanisms and key...

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Detalles Bibliográficos
Autores principales: Hou, Yutong, Lin, Sihao, Xia, Jia, Zhang, Yu, Yin, Yanan, Huang, Masha, Xu, Yingjie, Yang, Wen, Zhu, Yingjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652142/
https://www.ncbi.nlm.nih.gov/pubmed/38028193
http://dx.doi.org/10.1016/j.omtn.2023.102067