Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO-1 signaling pathway

OBJECTIVE: To investigate the therapeutic potential of dimethyl fumarate (DMF) in improving erectile function of bilateral cavernous nerve injury (BCNI) rats, along with elucidating its underlying mechanisms. METHODS: A BCNI rat model was established by clamping bilateral cavernous nerve (CN). DMF w...

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Detalles Bibliográficos
Autores principales: Song, Guoda, Wang, Jiaxin, Liu, Jihong, Ruan, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652210/
https://www.ncbi.nlm.nih.gov/pubmed/37931471
http://dx.doi.org/10.1016/j.redox.2023.102938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652210/
https://www.ncbi.nlm.nih.gov/pubmed/37931471
http://dx.doi.org/10.1016/j.redox.2023.102938

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