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KLF4 suppresses the proliferation of perihilar cholangiocarcinoma by negatively regulating GDF15 and phosphorylating AKT

Krüppel-like factor 4 (KLF4) is a transcription factor which functions as a tumor suppressor or an oncogene in numerous types of solid tumors. However, its expression levels and function in perihilar cholangiocarcinoma (pCCA) have yet to be elucidated. In the present study, in order to investigate i...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoming, Wang, Weijia, Lu, Chunlei, Zhang, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652240/
https://www.ncbi.nlm.nih.gov/pubmed/37937607
http://dx.doi.org/10.3892/or.2023.8659