Downregulation of TRPC6 regulates ERK1/2 to prevent sublytic C5b‑9 complement complex‑induced podocyte injury through activating autophagy

Idiopathic membranous nephropathy (IMN) is a common glomerular disease, in which 50-60% of patients can progress to end-stage renal disease within 10-20 years, seriously endangering human health. Podocyte injury is the direct cause of IMN. Sublytic C5b-9 complement complex induces damage in podocyte...

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Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Fang, Youfu, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652242/
https://www.ncbi.nlm.nih.gov/pubmed/38023364
http://dx.doi.org/10.3892/etm.2023.12275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652242/
https://www.ncbi.nlm.nih.gov/pubmed/38023364
http://dx.doi.org/10.3892/etm.2023.12275

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