Collective and Coordinated Conformational Changes Determine Agonism or Antagonism at the Human Trace Amine-Associated Receptor 1

[Image: see text] The human trace amine-associated receptor (hTAAR1), a G protein-coupled receptor, has been postulated as a new target in the treatment of neuropsychiatric conditions. The mechanism associated with activation or inactivation by agonists or antagonists in hTAAR1 and other GPCRs has n...

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Detalles Bibliográficos
Autores principales: Robles, Agustín I., Dinamarca-Villarroel, Luis, Torres, Gonzalo E., Fierro, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652269/
https://www.ncbi.nlm.nih.gov/pubmed/38024694
http://dx.doi.org/10.1021/acsomega.3c06315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652269/
https://www.ncbi.nlm.nih.gov/pubmed/38024694
http://dx.doi.org/10.1021/acsomega.3c06315

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