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Collective and Coordinated Conformational Changes Determine Agonism or Antagonism at the Human Trace Amine-Associated Receptor 1
[Image: see text] The human trace amine-associated receptor (hTAAR1), a G protein-coupled receptor, has been postulated as a new target in the treatment of neuropsychiatric conditions. The mechanism associated with activation or inactivation by agonists or antagonists in hTAAR1 and other GPCRs has n...
Autores principales: | Robles, Agustín I., Dinamarca-Villarroel, Luis, Torres, Gonzalo E., Fierro, Angélica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652269/ https://www.ncbi.nlm.nih.gov/pubmed/38024694 http://dx.doi.org/10.1021/acsomega.3c06315 |
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