Cargando…

Collective and Coordinated Conformational Changes Determine Agonism or Antagonism at the Human Trace Amine-Associated Receptor 1

[Image: see text] The human trace amine-associated receptor (hTAAR1), a G protein-coupled receptor, has been postulated as a new target in the treatment of neuropsychiatric conditions. The mechanism associated with activation or inactivation by agonists or antagonists in hTAAR1 and other GPCRs has n...

Descripción completa

Detalles Bibliográficos
Autores principales: Robles, Agustín I., Dinamarca-Villarroel, Luis, Torres, Gonzalo E., Fierro, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652269/
https://www.ncbi.nlm.nih.gov/pubmed/38024694
http://dx.doi.org/10.1021/acsomega.3c06315

Ejemplares similares