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Iron overload induces cerebral endothelial senescence in aged mice and in primary culture in a sex‐dependent manner

Iron imbalance in the brain negatively affects brain function. With aging, iron levels increase in the brain and contribute to brain damage and neurological disorders. Changes in the cerebral vasculature with aging may enhance iron entry into the brain parenchyma, leading to iron overload and its de...

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Detalles Bibliográficos
Autores principales: Noh, Brian, Blasco‐Conesa, Maria Pilar, Rahman, Syed Mushfiqur, Monga, Sheelu, Ritzel, Rodney, Guzman, Gary, Lai, Yun‐Ju, Ganesh, Bhanu Priya, Urayama, Akihiko, McCullough, Louise D., Moruno‐Manchon, Jose Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652299/
https://www.ncbi.nlm.nih.gov/pubmed/37675802
http://dx.doi.org/10.1111/acel.13977