STAT3 modulates CD4 (+) T mitochondrial dynamics and function in aging

Aging promotes numerous intracellular changes in T cells that impact their effector function. Our data show that aging promotes an increase in the localization of STAT3 to the mitochondria (mitoSTAT3), which promotes changes in mitochondrial dynamics and function and T‐cell cytokine production. Mech...

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Detalles Bibliográficos
Autores principales: Zukowski, Emelia, Sannella, Marco, Rockhold, Jack Donato, Kalantar, Gabriella H., Yu, Jingting, SantaCruz‐Calvo, Sara, Kuhn, Madison K., Hah, Nasun, Ouyang, Ling, Wang, Tzu‐Wen, Murphy, Lyanne, Marszalkowski, Heather, Gibney, Kaleigh, Drummond, Micah J., Proctor, Elizabeth A., Hasturk, Hatice, Nikolajczyk, Barbara S., Bharath, Leena P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652300/
https://www.ncbi.nlm.nih.gov/pubmed/37837188
http://dx.doi.org/10.1111/acel.13996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652300/
https://www.ncbi.nlm.nih.gov/pubmed/37837188
http://dx.doi.org/10.1111/acel.13996

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