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Drug repositioning strategy for the identification of novel telomere‐damaging agents: A role for NAMPT inhibitors

Drug repositioning strategy represents a valid tool to accelerate the pharmacological development through the identification of new applications for already existing compounds. In this view, we aimed at discovering molecules able to trigger telomere‐localized DNA damage and tumor cell death. By appl...

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Detalles Bibliográficos
Autores principales: Rizzo, Angela, Maresca, Carmen, D'Angelo, Carmen, Porru, Manuela, Di Vito, Serena, Salvati, Erica, Sacconi, Andrea, Berardinelli, Francesco, Sgura, Antonella, Kuznetsov, Sergey, Potdar, Swapnil, Hassinen, Antti, Stoppacciaro, Antonella, Zizza, Pasquale, Biroccio, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652301/
https://www.ncbi.nlm.nih.gov/pubmed/37858982
http://dx.doi.org/10.1111/acel.13944