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IL‐21‐IgFc immunotherapy alters transcriptional landscape of lymph node cells leading to enhanced flu vaccine response in aging and SIV infection
Aging people living with HIV (PWH) frequently manifest impaired antibody (Ab) responses to seasonal flu vaccination which has been attributed to ongoing inflammation and immune activation. We have recently reported a similar scenario in old simian immunodeficiency virus (SIV) infected rhesus macaque...
Autores principales: | Pallikkuth, Suresh, Kvistad, Daniel, Sirupangi, Tirupataiah, Kizhner, Alexander, Pahwa, Rajendra, Cameron, Mark J., Richardson, Brian, Williams, Sion, Ayupe, Ana, Brooks, Marissa, Petrovas, Constantinos, Villinger, Francois, Pahwa, Savita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652303/ https://www.ncbi.nlm.nih.gov/pubmed/37712598 http://dx.doi.org/10.1111/acel.13984 |
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