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The tumor suppressive effect and apoptotic mechanism of TRAIL gene‐containing recombinant NDV in TRAIL‐resistant colorectal cancer HT‐29 cells and TRAIL‐nonresistant HCT116 cells, with each cell bearing a mouse model

BACKGROUND: TRAIL is an anticancer drug that induces cancer cell apoptosis by interacting with death receptors (DRs). However, owing to low cell‐surface expression of DRs, certain colorectal cancer (CRC) cells resist TRAIL‐induced apoptosis. Newcastle disease virus (NDV) infection can elevate DR pro...

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Detalles Bibliográficos
Autores principales: Jung, Bo‐Kyoung, An, Yong Hee, Jang, Sung Hoon, Ryu, Gyoungah, Jung, Saet‐byel, Kim, Seonhee, Kim, Cuk‐Seong, Jang, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652305/
https://www.ncbi.nlm.nih.gov/pubmed/37843231
http://dx.doi.org/10.1002/cam4.6622