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Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction‐induced cellular senescence in dermal fibroblasts

Aging is accompanied by impaired mitochondrial function and accumulation of senescent cells. Mitochondrial dysfunction contributes to senescence by increasing the levels of reactive oxygen species and compromising energy metabolism. Senescent cells secrete a senescence‐associated secretory phenotype...

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Detalles Bibliográficos
Autores principales: Song, Min Ji, Park, Chi‐Hyun, Kim, Haesoo, Han, Sangbum, Lee, Si Hyung, Lee, Dong Hun, Chung, Jin Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652321/
https://www.ncbi.nlm.nih.gov/pubmed/37828898
http://dx.doi.org/10.1111/acel.14000