ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal neurodegenerative disorders that share pathological features, including the aberrant accumulation of ubiquitinated protein inclusions within motor neurons. Previously, we have shown that the sequestration of ubiquitin (U...

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Detalles Bibliográficos
Autores principales: Farrawell, Natalie E, Bax, Monique, McAlary, Luke, McKenna, Jessie, Maksour, Simon, Do-Ha, Dzung, Rayner, Stephanie L, Blair, Ian P, Chung, Roger S, Yerbury, Justin J, Ooi, Lezanne, Saunders, Darren N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652331/
https://www.ncbi.nlm.nih.gov/pubmed/37220877
http://dx.doi.org/10.1093/hmg/ddad063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652331/
https://www.ncbi.nlm.nih.gov/pubmed/37220877
http://dx.doi.org/10.1093/hmg/ddad063

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