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Cumulus expansion is impaired with advanced reproductive age due to loss of matrix integrity and reduced hyaluronan

Reproductive aging is associated with ovulatory defects. Age‐related ovarian fibrosis partially contributes to this phenotype as short‐term treatment with anti‐fibrotic compounds improves ovulation in reproductively old mice. However, age‐dependent changes that are intrinsic to the follicle may also...

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Detalles Bibliográficos
Autores principales: Babayev, Elnur, Suebthawinkul, Chanakarn, Gokyer, Dilan, Parkes, Wendena S., Rivas, Felipe, Pavone, Mary Ellen, Hall, Adam R., Pritchard, Michele T., Duncan, Francesca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652338/
https://www.ncbi.nlm.nih.gov/pubmed/37850336
http://dx.doi.org/10.1111/acel.14004