Cargando…

Proteomic architecture of frailty across the spectrum of cardiovascular disease

While frailty is a prominent risk factor in an aging population, the underlying biology of frailty is incompletely described. Here, we integrate 979 circulating proteins across a wide range of physiologies with 12 measures of frailty in a prospective discovery cohort of 809 individuals with severe a...

Descripción completa

Detalles Bibliográficos
Autores principales: Perry, Andrew S., Zhao, Shilin, Gajjar, Priya, Murthy, Venkatesh L., Lehallier, Benoit, Miller, Patricia, Nair, Sangeeta, Neill, Colin, Carr, J. Jeffrey, Fearon, William, Kapadia, Samir, Kumbhani, Dharam, Gillam, Linda, Lindenfeld, JoAnn, Farrell, Laurie, Marron, Megan M., Tian, Qu, Newman, Anne B., Murabito, Joanne, Gerszten, Robert E., Nayor, Matthew, Elmariah, Sammy, Lindman, Brian R., Shah, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652351/
https://www.ncbi.nlm.nih.gov/pubmed/37731195
http://dx.doi.org/10.1111/acel.13978