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Proteomic architecture of frailty across the spectrum of cardiovascular disease
While frailty is a prominent risk factor in an aging population, the underlying biology of frailty is incompletely described. Here, we integrate 979 circulating proteins across a wide range of physiologies with 12 measures of frailty in a prospective discovery cohort of 809 individuals with severe a...
Autores principales: | Perry, Andrew S., Zhao, Shilin, Gajjar, Priya, Murthy, Venkatesh L., Lehallier, Benoit, Miller, Patricia, Nair, Sangeeta, Neill, Colin, Carr, J. Jeffrey, Fearon, William, Kapadia, Samir, Kumbhani, Dharam, Gillam, Linda, Lindenfeld, JoAnn, Farrell, Laurie, Marron, Megan M., Tian, Qu, Newman, Anne B., Murabito, Joanne, Gerszten, Robert E., Nayor, Matthew, Elmariah, Sammy, Lindman, Brian R., Shah, Ravi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652351/ https://www.ncbi.nlm.nih.gov/pubmed/37731195 http://dx.doi.org/10.1111/acel.13978 |
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