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Mutational Landscape and In-Silico Analysis of TP53, PIK3CA, and PTEN in Patients with Breast Cancer from Khyber Pakhtunkhwa

[Image: see text] Herein, we report the mutational spectrum of three breast cancer candidate genes (TP53, PIK3CA, and PTEN) using WES for identifying potential biomarkers. The WES data were thoroughly analyzed using SAMtools for variant calling and identification of the mutations. Various bioinforma...

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Detalles Bibliográficos
Autores principales: Ahmad, Hilal, Ali, Asif, Ali, Roshan, Khalil, Ali Talha, Khan, Ishaq, Khan, Mah Muneer, Alorini, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652387/
https://www.ncbi.nlm.nih.gov/pubmed/38024667
http://dx.doi.org/10.1021/acsomega.3c07472