Concepts of multi-level dynamical modelling: understanding mechanisms of squamous cell carcinoma development in Fanconi anemia

Fanconi anemia (FA) is a rare disease (incidence of 1:300,000) primarily based on the inheritance of pathogenic variants in genes of the FA/BRCA (breast cancer) pathway. These variants ultimately reduce the functionality of different proteins involved in the repair of DNA interstrand crosslinks and...

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Detalles Bibliográficos
Autores principales: Velleuer, Eunike, Domínguez-Hüttinger, Elisa, Rodríguez, Alfredo, Harris, Leonard A., Carlberg, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652399/
https://www.ncbi.nlm.nih.gov/pubmed/38028610
http://dx.doi.org/10.3389/fgene.2023.1254966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652399/
https://www.ncbi.nlm.nih.gov/pubmed/38028610
http://dx.doi.org/10.3389/fgene.2023.1254966

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