Proteostasis and neurodegeneration: a closer look at autophagy in Alzheimer's disease

Alzheimer's disease (AD) is characterized by the accumulation of misfolded amyloid-beta and tau proteins. Autophagy acts as a proteostasis process to remove protein clumps, although it progressively weakens with aging and AD, thus facilitating the accumulation of toxic proteins and causing neur...

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Detalles Bibliográficos
Autores principales: Barmaki, Haleh, Nourazarian, Alireza, Khaki-Khatibi, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652403/
https://www.ncbi.nlm.nih.gov/pubmed/38020769
http://dx.doi.org/10.3389/fnagi.2023.1281338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652403/
https://www.ncbi.nlm.nih.gov/pubmed/38020769
http://dx.doi.org/10.3389/fnagi.2023.1281338

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