Cargando…

Proteostasis and neurodegeneration: a closer look at autophagy in Alzheimer's disease

Alzheimer's disease (AD) is characterized by the accumulation of misfolded amyloid-beta and tau proteins. Autophagy acts as a proteostasis process to remove protein clumps, although it progressively weakens with aging and AD, thus facilitating the accumulation of toxic proteins and causing neur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barmaki, Haleh, Nourazarian, Alireza, Khaki-Khatibi, Fatemeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652403/ https://www.ncbi.nlm.nih.gov/pubmed/38020769 http://dx.doi.org/10.3389/fnagi.2023.1281338

Ejemplares similares

Evaluation of dihydrotestosterone and dihydroprogesterone levels and gene expression of genes involved in neurosteroidogenesis in the SH-SY5Y Alzheimer disease cell model
por: Radagdam, Saeed, et al.
Publicado: (2023)

Editorial: Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches
por: Duran-Aniotz, Claudia, et al.
Publicado: (2022)

The Rhesus Macaque as a Translational Model for Neurodegeneration and Alzheimer’s Disease
por: Stonebarger, Gail A., et al.
Publicado: (2021)

Microglial autophagy in Alzheimer’s disease and Parkinson’s disease
por: Wang, Zhifu, et al.
Publicado: (2023)

Editorial: Infection, inflammation, and neurodegeneration: A critical path to Alzheimer's disease, Volume II
por: Mancuso, Roberta, et al.
Publicado: (2022)

Evaluation of the serum levels of Mannose binding lectin‐2, tenascin‐C, and total antioxidant capacity in patients with coronary artery disease
por: Mehri, Hamed, et al.
Publicado: (2021)

Temperature-Dependent Regulation of Proteostasis and Longevity
por: Vakkayil, Kavya Leo, et al.
Publicado: (2022)

Long-term social isolation stress exacerbates sex-specific neurodegeneration markers in a natural model of Alzheimer’s disease
por: Oliva, Carolina A., et al.
Publicado: (2023)

Proteostasis in striatal cells and selective neurodegeneration in Huntington’s disease
por: Margulis, Julia, et al.
Publicado: (2014)

Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
por: Lu, Ranran, et al.
Publicado: (2022)

The Intestine as a Lifespan- and Proteostasis-Promoting Signaling Tissue
por: Hodge, Francesca, et al.
Publicado: (2022)

Autophagy Impairment in App Knock-in Alzheimer’s Model Mice
por: Jiang, Richeng, et al.
Publicado: (2022)

Insights Into the Links Between Proteostasis and Aging From C. elegans
por: Zhang, William Hongyu, et al.
Publicado: (2022)

Proteostasis unbalance in prion diseases: Mechanisms of neurodegeneration and therapeutic targets
por: Thellung, Stefano, et al.
Publicado: (2022)

A Closer Look at Corticothalamic “Loops”
por: Rockland, Kathleen S.
Publicado: (2021)

Editorial: Exploring the role of exosomes in disease progression and therapeutics in neurodegeneration
por: Jan, Arif Tasleem, et al.
Publicado: (2023)

Neuroinflammation and neurodegeneration in diabetic retinopathy
por: Bianco, Lorenzo, et al.
Publicado: (2022)

Editorial: Genomic Instability and Neurodegeneration
por: Fuchs, Julia, et al.
Publicado: (2022)

Can exposure to heat attenuate neurodegeneration in older adults with Parkinson's disease?
por: Clark, Cayla E., et al.
Publicado: (2023)

Potential roles of oxidative distress on neurodegeneration in Parkinson's disease with neuropsychiatric symptoms
por: Li, Dan-ning, et al.
Publicado: (2022)

Editorial: Down Syndrome, Neurodegeneration and Dementia
por: Mufson, Elliott J., et al.
Publicado: (2021)

BACE1 and SCD1 are associated with neurodegeneration
por: Bedoya-Guzmán, Ferley A., et al.
Publicado: (2023)

Editorial: Novel mechanisms involved in aging and neurodegeneration: Seeking potential therapeutic targets for neurodegenerative diseases
por: Sanhueza, Mario, et al.
Publicado: (2022)

Motor Neuron Diseases and Neuroprotective Peptides: A Closer Look to Neurons
por: Zuccaro, Emanuela, et al.
Publicado: (2021)

Prohibitins in neurodegeneration and mitochondrial homeostasis
por: Fernandez-Abascal, Jesus, et al.
Publicado: (2022)

The role of microglial autophagy in Parkinson’s disease
por: Zhu, Rui, et al.
Publicado: (2022)

Fibroblast Growth Factor 21 Modulates Microglial Polarization That Attenuates Neurodegeneration in Mice and Cellular Models of Parkinson's Disease
por: Yang, Changwei, et al.
Publicado: (2021)

The Big Picture of Neurodegeneration: A Meta Study to Extract the Essential Evidence on Neurodegenerative Diseases in a Network-Based Approach
por: Ruffini, Nicolas, et al.
Publicado: (2022)

Alzheimer’s disease: an axonal injury disease?
por: Dan, Liang, et al.
Publicado: (2023)

Mechanisms underlying TDP-43 pathology and neurodegeneration: An updated Mini-Review
por: Nilaver, Benjamin I., et al.
Publicado: (2023)

Editorial: Glaucoma and Brain: Impact of Neurodegeneration on Visual Abilities and Related Biomarkers
por: Rolle, Teresa, et al.
Publicado: (2022)

Editorial: The UN international day of families: neurodegeneration as a result of genetic inheritance
por: Pacheva, Iliyana Hristova, et al.
Publicado: (2023)

Tau kinetics in Alzheimer's disease
por: Hier, Daniel B., et al.
Publicado: (2022)

Investigation of serum levels of orexin‐A, transforming growth factor β, and leptin in patients with multiple sclerosis
por: Moharami, Sepideh, et al.
Publicado: (2021)

Details of the Construction of Perception: A Closer Look at Illusory Contours
por: Eriksson, Johan, et al.
Publicado: (2009)

Editorial: Advances in connectome-wide association studies (CWAS) along the neurodegeneration trajectory
por: Ye, Chenfei, et al.
Publicado: (2023)

The Role of Alpha-Synuclein Autoantibodies in the Induction of Brain Inflammation and Neurodegeneration in Aged Humans
por: Pandey, Manoj Kumar
Publicado: (2022)

Editorial: Systemic implications of Alzheimer's disease
por: Cortes, Constanza J., et al.
Publicado: (2023)

Alzheimer’s Disease: An Update and Insights Into Pathophysiology
por: Abubakar, Murtala Bello, et al.
Publicado: (2022)

Benefits of dietary polyphenols in Alzheimer’s disease
por: El Gaamouch, Farida, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p23nugu2aqjruil0cv7m050jgr