Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer

BACKGROUND: The outcome of patients with colon cancer is still unsatisfied nowadays. Simvastatin is a type of statins with anti-cancer activity, but its effect on colon cancer cells remains unclear. The present study is intended to determine the underlying mechanism of simvastatin in treatment of co...

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Detalles Bibliográficos
Autores principales: Xie, Wei, Peng, Mingjing, Liu, Ying, Zhang, Bocheng, Yi, Liang, Long, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652480/
https://www.ncbi.nlm.nih.gov/pubmed/37974278
http://dx.doi.org/10.1186/s12964-023-01359-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652480/
https://www.ncbi.nlm.nih.gov/pubmed/37974278
http://dx.doi.org/10.1186/s12964-023-01359-y

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