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Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer

BACKGROUND: The outcome of patients with colon cancer is still unsatisfied nowadays. Simvastatin is a type of statins with anti-cancer activity, but its effect on colon cancer cells remains unclear. The present study is intended to determine the underlying mechanism of simvastatin in treatment of co...

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Detalles Bibliográficos
Autores principales:	Xie, Wei, Peng, Mingjing, Liu, Ying, Zhang, Bocheng, Yi, Liang, Long, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652480/ https://www.ncbi.nlm.nih.gov/pubmed/37974278 http://dx.doi.org/10.1186/s12964-023-01359-y

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