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Differential role of RB in response to UV and IR damage
The retinoblastoma tumor suppressor (RB) is functionally inactivated in the majority of cancers and is a critical mediator of DNA damage checkpoints. Despite the critical importance of RB function in tumor suppression, the coordinate impact of RB loss on the response to environmental and therapeutic...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065251/ https://www.ncbi.nlm.nih.gov/pubmed/15767283 http://dx.doi.org/10.1093/nar/gki283 |