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What exactly does the PfK13 C580Y mutation in Plasmodium falciparum influence?

BACKGROUND: The emergence and spread of artemisinin resistance threaten global malaria control and elimination goals, and encourage research on the mechanisms of drug resistance in malaria parasites. Mutations in Plasmodium falciparum Kelch 13 (PfK13) protein are associated with artemisinin resistan...

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Detalles Bibliográficos
Autores principales: Si, Wenwen, Zhao, Yuemeng, Qin, Xixi, Huang, Yixuan, Yu, Jing, Liu, Xiao, Li, Yanna, Yan, Xiaoli, Zhang, Qingfeng, Sun, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652512/
https://www.ncbi.nlm.nih.gov/pubmed/37974285
http://dx.doi.org/10.1186/s13071-023-06024-4