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Mutation spectrum, expression profiling, and prognosis evaluation of Fanconi anemia signaling pathway genes for 4259 patients with myelodysplastic syndromes or acute myeloid leukemia

BACKGROUND: Individuals diagnosed with Fanconi anemia (FA), an uncommon disorder characterized by chromosomal instability affecting the FA signaling pathway, exhibit heightened vulnerability to the onset of myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). METHODS: Herein, we employed...

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Detalles Bibliográficos
Autores principales: Chang, Lixian, Zhang, Li, Zhao, Beibei, Cheng, Xuelian, Wan, Yang, Zhang, Ranran, Yuan, Weiping, Gao, Xingjie, Zhu, Xiaofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652513/
https://www.ncbi.nlm.nih.gov/pubmed/37974167
http://dx.doi.org/10.1186/s12920-023-01730-5