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Gene conversion and deletion frequencies during double-strand break repair in human cells are controlled by the distance between direct repeats
Homologous recombination (HR) repairs DNA double-strand breaks and maintains genome stability. HR between linked, direct repeats can occur by gene conversion without an associated crossover that maintains the gross repeat structure. Alternatively, direct repeat HR can occur by gene conversion with a...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065255/ https://www.ncbi.nlm.nih.gov/pubmed/15767282 http://dx.doi.org/10.1093/nar/gki295 |