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Gene conversion and deletion frequencies during double-strand break repair in human cells are controlled by the distance between direct repeats

Homologous recombination (HR) repairs DNA double-strand breaks and maintains genome stability. HR between linked, direct repeats can occur by gene conversion without an associated crossover that maintains the gross repeat structure. Alternatively, direct repeat HR can occur by gene conversion with a...

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Detalles Bibliográficos
Autores principales: Schildkraut, Ezra, Miller, Cheryl A., Nickoloff, Jac A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065255/
https://www.ncbi.nlm.nih.gov/pubmed/15767282
http://dx.doi.org/10.1093/nar/gki295