Immune signatures of the POLE mutation in endometrial carcinomas: a systematic study based on TCGA data and clinical cohort validation

BACKGROUND: POLE is a critical biomarker for endometrial cancer (ECs) prognosis and therapeutic decision. However, the immune infiltration and immunotherapy-related gene expression in the tumor microenvironment (TME) of POLE-mutated ECs remain unresolved. METHODS: The TCGA database was used to chara...

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Detalles Bibliográficos
Autores principales: Wang, Tieyan, Yu, Dan, Wang, Juanjuan, Zhu, Ningning, Tang, Xian-bin, Chen, Xiuwen, Su, Xiao-min, Huang, Yu-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652564/
https://www.ncbi.nlm.nih.gov/pubmed/38023184
http://dx.doi.org/10.3389/fonc.2023.1250558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652564/
https://www.ncbi.nlm.nih.gov/pubmed/38023184
http://dx.doi.org/10.3389/fonc.2023.1250558

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