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Microvesicles-hydrogel breaks the cycle of cellular senescence by improving mitochondrial function to treat osteoarthritis

BACKGROUND: Osteoarthritis (OA) is an age-related disease characterised by the accumulation of senescent chondrocytes, which drives its pathogenesis and progression. Senescent cells exhibit distinct features, including mitochondrial dysfunction and the excessive accumulation and release of reactive...

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Detalles Bibliográficos
Autores principales: Liu, Senrui, Cheng, Shengwen, Chen, Bowen, Xiao, Pengcheng, Zhan, Jingdi, Liu, Jiacheng, Chen, Zhuolin, Liu, Junyan, Zhang, Tao, Lei, Yiting, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652587/
https://www.ncbi.nlm.nih.gov/pubmed/37968657
http://dx.doi.org/10.1186/s12951-023-02211-8