Structural roles of CTG repeats in slippage expansion during DNA replication

CTG triplet repeat sequences have been found to form slipped-strand structures leading to self-expansion during DNA replication. The lengthening of these repeats causes the onset of neurodegenerative diseases, such as myotonic dystrophy. In this study, electrophoretic and NMR spectroscopic studies h...

Descripción completa

Detalles Bibliográficos
Autores principales: Chi, Lai Man, Lam, Sik Lok
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065260/
https://www.ncbi.nlm.nih.gov/pubmed/15767285
http://dx.doi.org/10.1093/nar/gki307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065260/
https://www.ncbi.nlm.nih.gov/pubmed/15767285
http://dx.doi.org/10.1093/nar/gki307

Ejemplares similares