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Exploring Novel Vitamin K Derivatives with Anti-SARS-CoV-2 Activity

[Image: see text] From our compound library of vitamin K derivatives, we found that some compounds exhibited anti-SARS-CoV-2 activity in VeroE6/TMPRSS2 cells. The common structure of these compounds was menaquinone-2 (MK-2) with either the m-methylphenyl or the 1-naphthyl group introduced at the end...

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Detalles Bibliográficos
Autores principales: Homma, Taiki, Okamoto, Mika, Koharazawa, Ryohto, Hayakawa, Mayu, Fushimi, Taiki, Tode, Chisato, Hirota, Yoshihisa, Osakabe, Naomi, Baba, Masanori, Suhara, Yoshitomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652723/
https://www.ncbi.nlm.nih.gov/pubmed/38024673
http://dx.doi.org/10.1021/acsomega.3c04175