Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases

Most mitochondrial proteins are targeted to the organelle by N-terminal mitochondrial targeting sequences (MTSs, or “presequences”) that are recognized by the import machinery and subsequently cleaved to yield the mature protein. MTSs do not have conserved amino acid compositions, but share common p...

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Detalles Bibliográficos
Autores principales: Reed, Ashley L., Mitchell, Wayne, Alexandrescu, Andrei T., Alder, Nathan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652799/
https://www.ncbi.nlm.nih.gov/pubmed/38028797
http://dx.doi.org/10.3389/fphys.2023.1263420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652799/
https://www.ncbi.nlm.nih.gov/pubmed/38028797
http://dx.doi.org/10.3389/fphys.2023.1263420

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