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Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases
Most mitochondrial proteins are targeted to the organelle by N-terminal mitochondrial targeting sequences (MTSs, or “presequences”) that are recognized by the import machinery and subsequently cleaved to yield the mature protein. MTSs do not have conserved amino acid compositions, but share common p...
Autores principales: | Reed, Ashley L., Mitchell, Wayne, Alexandrescu, Andrei T., Alder, Nathan N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652799/ https://www.ncbi.nlm.nih.gov/pubmed/38028797 http://dx.doi.org/10.3389/fphys.2023.1263420 |
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