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MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

Cellular stress in the form of disrupted transcription, loss of organelle integrity, or damage to nucleic acids can elicit inflammatory responses by activating signaling cascades canonically tasked with controlling pathogen infections. These stressors must be kept in check to prevent unscheduled act...

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Detalles Bibliográficos
Autores principales: Smith, Julian R., Dowling, Jack W., McFadden, Matthew I., Karp, Andrew, Schwerk, Johannes, Woodward, Joshua J., Savan, Ram, Forero, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652867/
https://www.ncbi.nlm.nih.gov/pubmed/37467105
http://dx.doi.org/10.1016/j.celrep.2023.112805