A comprehensive approach to developing a multi-epitope vaccine against Mycobacterium tuberculosis: from in silico design to in vitro immunization evaluation

INTRODUCTION: The Bacillus Calmette-Guérin (BCG) vaccine, currently used against tuberculosis (TB), exhibits inconsistent efficacy, highlighting the need for more potent TB vaccines. MATERIALS AND METHODS: In this study, we employed reverse vaccinology techniques to develop a promising multi-epitope...

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Detalles Bibliográficos
Autores principales: Jiang, Fan, Han, Yong, Liu, Yinping, Xue, Yong, Cheng, Peng, Xiao, Li, Gong, Wenping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652892/
https://www.ncbi.nlm.nih.gov/pubmed/38022558
http://dx.doi.org/10.3389/fimmu.2023.1280299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652892/
https://www.ncbi.nlm.nih.gov/pubmed/38022558
http://dx.doi.org/10.3389/fimmu.2023.1280299

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