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Bhlhe40 limits early IL-10 production from CD4(+) T cells during Plasmodium yoelii 17X infection

The cytokine IL-10 suppresses T-cell-mediated immunity, which is required to control infection with Plasmodium yoelii. Consequently, IL-10 can delay the time needed to resolve this infection, leading to a higher parasite burden. While the pathways that lead to IL-10 production by CD4(+) T cells are...

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Detalles Bibliográficos
Autores principales: O'Neal, Kara A., Zeltner, Sheldon L., Foscue, Camille L., Stumhofer, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652903/
https://www.ncbi.nlm.nih.gov/pubmed/37843306
http://dx.doi.org/10.1128/iai.00367-23