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Clonal germinal center B cells function as a niche for T-cell lymphoma
Angioimmunoblastic T-cell lymphoma (AITL) is proposed to be initiated by age-related clonal hematopoiesis (ACH) with TET2 mutations, whereas the G17V RHOA mutation in immature cells with TET2 mutations promotes the development of T follicular helper (T(FH))-like tumor cells. Here, we investigated th...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653021/ https://www.ncbi.nlm.nih.gov/pubmed/35921527 http://dx.doi.org/10.1182/blood.2022015451 |