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Clonal germinal center B cells function as a niche for T-cell lymphoma
Angioimmunoblastic T-cell lymphoma (AITL) is proposed to be initiated by age-related clonal hematopoiesis (ACH) with TET2 mutations, whereas the G17V RHOA mutation in immature cells with TET2 mutations promotes the development of T follicular helper (T(FH))-like tumor cells. Here, we investigated th...
Autores principales: | Fujisawa, Manabu, Nguyen, Tran B., Abe, Yoshiaki, Suehara, Yasuhito, Fukumoto, Kota, Suma, Sakurako, Makishima, Kenichi, Kaneko, Chihiro, Nguyen, Yen T.M., Usuki, Kensuke, Narita, Kentaro, Matsue, Kosei, Nakamura, Naoya, Ishikawa, Shumpei, Miura, Fumihito, Ito, Takashi, Suzuki, Ayako, Suzuki, Yutaka, Mizuno, Seiya, Takahashi, Satoru, Chiba, Shigeru, Sakata-Yanagimoto, Mamiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653021/ https://www.ncbi.nlm.nih.gov/pubmed/35921527 http://dx.doi.org/10.1182/blood.2022015451 |
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