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Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude

Studies have shown significantly increased thromboembolic events at high altitude. We recently reported that transferrin could potentiate blood coagulation, but the underlying mechanism for high altitude–related thromboembolism is still poorly understood. Here, we examined the activity and concentra...

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Detalles Bibliográficos
Autores principales: Li, Meiquan, Tang, Xiaopeng, Liao, Zhiyi, Shen, Chuanbin, Cheng, Ruomei, Fang, Mingqian, Wang, Gan, Li, Ya, Tang, Shuzhen, Xie, Li, Zhang, Zhiye, Kamau, Peter Muiruri, Mwangi, James, Lu, Qiumin, Li, Yaxiong, Wang, Yuming, MacKeigan, Daniel Thomas, Cerenzia, Eric G., Ni, Heyu, Lai, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653030/
https://www.ncbi.nlm.nih.gov/pubmed/36040436
http://dx.doi.org/10.1182/blood.2022016410