GARP-mediated active TGF-β1 induces bone marrow NK cell dysfunction in AML patients with early relapse post–allo-HSCT

Relapse is a leading cause of death after allogeneic hematopoietic stem cell transplantation (allo-HSCT) for acute myeloid leukemia (AML). However, the underlying mechanisms remain poorly understood. Natural killer (NK) cells play a crucial role in tumor surveillance and cancer immunotherapy, and NK...

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Detalles Bibliográficos
Autores principales: Wang, Dongyao, Sun, Zimin, Zhu, Xiaoyu, Zheng, Xiaohu, Zhou, Yonggang, Lu, Yichen, Yan, Peidong, Wang, Huiru, Liu, Huilan, Jin, Jing, Zhu, Huaiping, Sun, Rui, Wang, Yi, Fu, Binqing, Tian, Zhigang, Wei, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653097/
https://www.ncbi.nlm.nih.gov/pubmed/35981475
http://dx.doi.org/10.1182/blood.2022015474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653097/
https://www.ncbi.nlm.nih.gov/pubmed/35981475
http://dx.doi.org/10.1182/blood.2022015474

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