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Severe osteoarthritis at unexpected age
INTRODUCTION: Acromegaly is a rare chronic endocrine disease caused by a growth hormone (GH) – producing adenoma, resulting in elevated GH and insulin-like growth factor-1 (IGF-1) concentrations. GH and IGF-1 are essential for normal growth, differentiation, and repair of cartilage and bone; however...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653152/ http://dx.doi.org/10.1210/jcemcr/luac014.014 |