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The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4(+)CD25(+ )T cells

It is now generally accepted that CD4(+)CD25(+ )T(reg )cells play a major role in the prevention of autoimmunity and pathological immune responses. Their involvement in the pathogenesis of chronic arthritis is controversial, however, and so we examined their role in experimental antigen-induced arth...

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Detalles Bibliográficos
Autores principales: Frey, Oliver, Petrow, Peter K, Gajda, Mieczyslaw, Siegmund, Kerstin, Huehn, Jochen, Scheffold, Alexander, Hamann, Alf, Radbruch, Andreas, Bräuer, Rolf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065322/
https://www.ncbi.nlm.nih.gov/pubmed/15743476
http://dx.doi.org/10.1186/ar1484