Endoplasmic Reticulum Stress Disrupts Mitochondrial Bioenergetics, Dynamics and Causes Corneal Endothelial Cell Apoptosis

PURPOSE: Endoplasmic reticulum (ER) and mitochondrial stress are independently associated with corneal endothelial cell (CEnC) loss in many corneal diseases, including Fuchs’ endothelial corneal dystrophy (FECD). However, the role of ER stress in mitochondrial dysfunction contributing to CEnC apopto...

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Detalles Bibliográficos
Autores principales: Qureshi, Saba, Lee, Stephanie, Steidl, William, Ritzer, Lukas, Parise, Michael, Chaubal, Ananya, Kumar, Varun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653263/
https://www.ncbi.nlm.nih.gov/pubmed/37962528
http://dx.doi.org/10.1167/iovs.64.14.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653263/
https://www.ncbi.nlm.nih.gov/pubmed/37962528
http://dx.doi.org/10.1167/iovs.64.14.18

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