Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production

The mechanism of endothelin-1 (ET-1)-induced nitric oxide (NO) production, MMP-1 production and MMP-13 production was investigated in human osteoarthritis chondrocytes. The cells were isolated from human articular cartilage obtained at surgery and were cultured in the absence or presence of ET-1 wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Manacu, Christina Alexandra, Martel-Pelletier, Johanne, Roy-Beaudry, Marjolaine, Pelletier, Jean-Pierre, Fernandes, Julio C, Shipkolye, Fazool S, Mitrovic, Dragoslav R, Moldovan, Florina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065327/
https://www.ncbi.nlm.nih.gov/pubmed/15743480
http://dx.doi.org/10.1186/ar1489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065327/
https://www.ncbi.nlm.nih.gov/pubmed/15743480
http://dx.doi.org/10.1186/ar1489

Ejemplares similares