Hepatic mitochondrial NAD(+) transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis

BACKGROUND & AIMS: SLC25A47 was initially identified as a mitochondrial HCC-downregulated carrier protein, but its physiological functions and transport substrates are unknown. We aimed to investigate the physiological role of SLC25A47 in hepatic metabolism. APPROACH & RESULTS: In the treatm...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Lili, Deepak, R.N.V. Krishna, Wang, Guoqiang, Meng, Ziyi, Tao, Lei, Xie, Mengqing, Chi, Wenna, Zhang, Yuming, Yang, Mingming, Liao, Yilie, Chen, Ruiqun, Liang, Yu, Zhang, Junyu, Huang, Yuedong, Wang, Weihua, Guo, Zhiying, Wang, Yunfang, Lin, Jiandie D., Fan, Hao, Chen, Ligong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles: Steatohepatitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653290/
https://www.ncbi.nlm.nih.gov/pubmed/36804859
http://dx.doi.org/10.1097/HEP.0000000000000314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653290/
https://www.ncbi.nlm.nih.gov/pubmed/36804859
http://dx.doi.org/10.1097/HEP.0000000000000314

Ejemplares similares