Cargando…
Hepatic mitochondrial NAD(+) transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis
BACKGROUND & AIMS: SLC25A47 was initially identified as a mitochondrial HCC-downregulated carrier protein, but its physiological functions and transport substrates are unknown. We aimed to investigate the physiological role of SLC25A47 in hepatic metabolism. APPROACH & RESULTS: In the treatm...
Autores principales: | Cheng, Lili, Deepak, R.N.V. Krishna, Wang, Guoqiang, Meng, Ziyi, Tao, Lei, Xie, Mengqing, Chi, Wenna, Zhang, Yuming, Yang, Mingming, Liao, Yilie, Chen, Ruiqun, Liang, Yu, Zhang, Junyu, Huang, Yuedong, Wang, Weihua, Guo, Zhiying, Wang, Yunfang, Lin, Jiandie D., Fan, Hao, Chen, Ligong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653290/ https://www.ncbi.nlm.nih.gov/pubmed/36804859 http://dx.doi.org/10.1097/HEP.0000000000000314 |
Ejemplares similares
-
Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis
por: Yan, Tingting, et al.
Publicado: (2023) -
Relationship between NAFLD and coronary artery disease: A Mendelian randomization study
por: Ren, Zhewen, et al.
Publicado: (2023) -
The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review
por: Younossi, Zobair M., et al.
Publicado: (2023) -
Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism
por: Deprince, Audrey, et al.
Publicado: (2023) -
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
por: Afonso, Marta B., et al.
Publicado: (2023)