Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function

Oxidative stress leads to increased risk for osteoarthritis (OA) but the precise mechanism remains unclear. We undertook this study to clarify the impact of oxidative stress on the progression of OA from the viewpoint of oxygen free radical induced genomic instability, including telomere instability...

Descripción completa

Detalles Bibliográficos
Autores principales: Yudoh, Kazuo, van Trieu, Nguyen, Nakamura, Hiroshi, Hongo-Masuko, Kayo, Kato, Tomohiro, Nishioka, Kusuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065334/
https://www.ncbi.nlm.nih.gov/pubmed/15743486
http://dx.doi.org/10.1186/ar1499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065334/
https://www.ncbi.nlm.nih.gov/pubmed/15743486
http://dx.doi.org/10.1186/ar1499

Ejemplares similares