Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex

The mammalian tRNA ligase complex (tRNA-LC) catalyzes the splicing of intron-containing pre-tRNAs in the nucleus and the splicing of XBP1 mRNA during the unfolded protein response (UPR) in the cytoplasm. We recently reported that the tRNA-LC coevolved with PYROXD1, an essential oxidoreductase that p...

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Detalles Bibliográficos
Autores principales: Jaksch, Dhaarsini, Irnstorfer, Johanna, Kalman, Petra-Franziska, Martinez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653391/
https://www.ncbi.nlm.nih.gov/pubmed/37648453
http://dx.doi.org/10.1261/rna.079732.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653391/
https://www.ncbi.nlm.nih.gov/pubmed/37648453
http://dx.doi.org/10.1261/rna.079732.123

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